A Nano Empire AI production
Optimistic takes on the AI news that matters. Deconstructing abundance, autonomous agents, frontier bio-tech, and the builders turning sci-fi into production infrastructure.
7 episodes published · Full audio stream
Jason Calacanis told the All-In besties that AI's biggest moment is coming for everyday Americans — agentic assistants are putting a free executive assistant in every pocket, and the bottom half of the K-shaped recovery is about to feel the boom. Maya and Dev ask the real ques...
Cathie Wood and Brett Winton made the case at Moonshots Live 2026 that curing disease is one of the best businesses of our time. Maya and Dev deconstruct the convergence — sequencing costs collapsing from $3B to under $100, AI reading the code of life, CRISPR editing it in liv...
David Friedberg told the All-In besties that the AI wars are already here — the software came before the robots. Maya and Dev deconstruct his case: why Fortune 50 boards just made cyber defense priority number one, why defending in the AI era means using AI, why the US cannot ...
Twenty-nine. That's the average age of an AI unicorn founder — down from forty just three years ago. Maya and Dev unpack the Moonshots Live story on AI's youth wave: the Antler data on sixteen hundred unicorns, Mercor's twenty-two-year-old billionaires, Alexandr Wang taking ov...
A mountain gorilla in Rwanda has a bank account — and an AI spends the money for it. Maya and Dev unpack Alex Wissner-Gross's Moonshots Live story: the physicist behind the 2013 "causal entropic forces" paper explains why he backed Tehanu, the startup building "interspecies mo...
Six of the world's most powerful CEOs walked into the White House and signed the Super Intelligence Accord. Maya and Dev deconstruct the All-In story of the week: the executive order rebranding AI as Super Intelligence, the voluntary safety pact with internal controls and exte...
Optimistic commentary on Moonshots EP #300, where Peter Diamandis interviews Astro Teller (Captain of Moonshots at X) on clean water at a penny a liter, moonshots getting 3x cheaper in 16 years, and the billion-dollar bet no CEO will back. Hosts Maya and Dev break down X's met...